What is high cystatin?
If you have an abnormally high concentration of cystatin C in your blood, it may mean you may have a kidney condition, such as chronic kidney disease. Higher levels of cystatin C may also be caused by diabetes, cancer, HIV, hyperthyroidism, or hypothyroidism.
How do you lower cystatin C naturally?
Lose weight if overweight. It may help bring down your cystatin C levels [85]. Smoking is associated with higher cystatin C levels. Quitting may help lower your levels, while supporting your overall health [85].
What is a good cystatin C level?
Normal serum creatinine values range from 0.6 to 1.3 mg/dl, and normal serum cystatin C values range from 0.6 to 1 mg/l.
Why is cystatin C better than creatinine?
Like serum creatinine, cystatin C concentrations were much more stable in individuals without renal disease than was GFR measured by creatinine clearance [5]. A possible advantage of cystatin C with minor glomerular damage is that, being a large molecule, blood levels of cystatin C might rise sooner than creatinine.
What happens if cystatin C is high?
If the level of cystatin C in your blood is too high, it may mean that your kidneys are not working well. A blood test for cystatin C can help your healthcare provider find your GFR (glomerular filtration rate).
How do you reduce cystatin?
Conclusion. We found that coffee consumption for 2 weeks decreased the serum cystatin C concentration and increased cystatin-C-based eGFR, along with favorable increases in serum adiponectin and magnesium concentrations in healthy young adults.
What fruit is good for kidneys?
If you have kidney disease, a variety of fruits can be beneficial to include in your diet as long as they don’t contain excessive amounts of potassium and phosphorus….Other fruits that may be recommended for promoting kidney health include:
- Pears.
- Peaches.
- Clementines.
- Nectarines.
- Mandarins.
- Plums.
- Satsumas.
- Watermelon.
What are the symptoms when creatinine is high?
Elevated Blood Creatinine Level – Symptoms However, common high creatinine symptoms are extreme unexplained fatigue and/or lethargy, dehydration, reduced urine output and/or darkened colour of urine, swelling over feet, face, under the eyes, etc.
Is there another name for cystatin C?
Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function.
What is cystatin C test used for?
This test measures the amount of cystatin C in blood to help evaluate kidney function. Cystatin C is filtered out of the blood by the glomeruli, clusters of tiny blood vessels in the kidneys that allow water, dissolved substances, and wastes to pass through their walls while retaining blood cells and larger proteins.
What is a normal GFR for a 70 year old?
However, we know that GFR physiologically decreases with age, and in adults older than 70 years, values below 60 mL/min/1.73 m2 could be considered normal.
What level of creatinine indicates kidney failure?
A GFR of 60 or over is considered normal, a GFR less than 60 may indicate kidney disease. A level of 15 or less is defined medically as kidney failure.
What do you need to know about cystatin C?
Cystatin C 1 What is cystatin C? Cystatin C is a protein that is produced by the cells in your body. 2 Your GFR tells a lot about how well your kidneys are… 3 Having a simple blood test for creatinine is the first step in checking your…
How is cystatin C broken down in the kidneys?
Cystatin C is almost completely broken down in the kidneys (>99%). In healthy people, both the production and the breakdown of this protein happen at a relatively constant rate. But if your kidneys are not working properly, cystatin C builds up in the blood [ 6, 7, 8 ]. That is why this molecule can tell us how well our kidneys are working.
Which is more accurate cystatin C or creatinine?
Cross-sectional studies (based on a single point in time) suggest that serum levels of cystatin C are a more precise test of kidney function (as represented by the glomerular filtration rate, GFR) than serum creatinine levels..
How does cystatin C affect hardening of the arteries?
Cystatin C levels are decreased in atherosclerotic (so-called ‘hardening’ of the arteries) and aneurysmal (saccular bulging) lesions of the aorta.