What is acantholytic dermatosis?

Abstract. Transient acantholytic dermatosis is a self-limited, primary acantholytic disease that occurs predominantly in persons over 50 years old. The primary lesions, discrete papules and papulovesicles, are distributed mainly on the chest, back, and thighs and may be intensely pruritic.

What is acantholytic dyskeratosis?

Background: Focal acantholytic dyskeratosis is a distinctive histologic pattern characterized by (1) suprabasilar clefts around preserved papillae, (2) acantholytic and dyskeratotic cells at all levels of the epidermis, and (3) hyperkeratosis and parakeratosis.

Can Grover’s disease affect the scalp?

Multiple, small, discrete, red-brown papules characteristic of Grover disease are present. Patients who are severely affected may have disseminated disease affecting the neck, the shoulders, the arms, and the legs. The scalp is usually not affected, and the palms and the soles are almost always spared.

How does Grover’s disease start?

Many cases have occurred in men who use hot tubs, steam rooms, electric blankets, and other warming items. It can also be caused by certain medications, organ transplants, kidney disease, Dialysis, or exposure to x rays.

Is Grover’s disease serious?

Grover’s disease is an uncommon but potentially debilitating skin condition. Doctors are not yet sure what causes the disease or how to cure it, but treatments are available to manage the symptoms. Also called transient acantholytic dermatosis, Grover’s disease typically presents as a rash on the chest and back.

What causes Grover’s disease to flare up?

For people who have more persistent cases associated with sun-damaged or dry skin, symptoms of Grover’s disease tend to come and go. In these individuals, the disease may flare when they are exposed to exacerbating factors such as high temperatures, sweating, or very dry skin.