What are SkBr3 cells?
SkBr3 (also known as SK-BR-3) is a human breast cancer cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970 that is used in therapeutic research, especially in context of HER2 targeting.
What is SUM159?
SUM159 is a mesenchymal triple-negative breast cancer cell line with high usefulness for many studies. Cells grow well in appropriate media with supplements. These cells were used to investigate the effects of novel inhibitors of signaling pathways (e.g. NF-kB).
Can an 11 year old have breast cancer?
Developing breast cancer when you’re a teenager is extremely rare. It’s also uncommon in women in their 20s and 30s. The vast majority of breast cancers are diagnosed in women over the age of 50.
What is HEK293?
Human embryonic kidney 293 (HEK293, HEK-293, or HEK) cells are one of the most common cell lines used for research purposes, second only to HeLa cells. Their popularity is due to several properties such as easy maintenance, robustness, and ease of transfection.
What type of cells are MCF7 cells?
MCF-7 is an adherent, epithelial luminal cell line positive for estrogen and progesterone receptors. Although they are referred to as hormone-dependent, the minimal amount of steroid hormones present in serum is sufficient to ensure cell growth.
Can 7 year old get breast cancer?
Breast cancer in children is very rare, but it can happen. When children have tumors in their breast tissue, they’re normally benign tumors called fibroadenomas. A child with fibroadenomas will need to be monitored but won’t need any treatments. Occasionally, children will have malignant breast tumors.
Is it normal for a 9 year old to have a lump in her breast?
The lump may be tender and sore, but it is completely normal in girls undergoing puberty. However, if your child is under eight years old and developing breast buds, she may be experiencing precocious puberty.
How is HER2 detected?
There are two established ways to test HER2 status: Immunohistochemistry (IHC) measures the amount of HER2 protein present. Fluorescent in situ hybridization (FISH) looks at the gene level for the number of copies of the gene present; an increased number of gene copies is known as amplification.