This novel combination further increases the superb resolution and mass accuracy of FTMS by using the latest proprietary high-field magnet technology, while adding facile and efficient precursor mass selection and collision induced dissociation in a conventional Qh "front end" for on-the-fly data-dependent MS/FTMS fragmentation, or selected accumulation of LC-separated protein digests.
The new high-field APEX-Q can deliver sub-ppm mass accuracy, enormous resolving power for peptide mixtures, wide bandwidth detection, high dynamic range, and fast automated data-dependent MS/MS for detailed proteome characterization when coupled on-line to liquid chromatography.
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